Endocrine Abstracts

Objective: Determination of changes in metabolic status and vitamin D, osteoprotegerin concentrations in obese children.Methods: We examined 212 children in the University Hospital from 2016 to 2018 yrs. Their anthropometric parameters (body mass index (BMI)) were determined. Blood levels of vitamin D, OPG, insulin were determined. In the biochemical blood test, the parameters of uric acid, glucose were evaluated. All children were divided into 2 groups:...

The use insulin pump therapy (IPT) (continuous subcutaneous insulin infusion (CSII)) has increased dramatically in youth with type 1 diabetes (T1D) in the past decade.Objective: Rate metabolic compensation of diabetes mellitus in children on IPT on the level HbA1c and self-control of glycaemia.Methods: The examination of 19 children aged 12.55±3.75 years (boys/girls=13/6), with T1D, observed in ‘2nd City Children’s H...

Aim: To assess changes of metabolic status in children with pituitary insufficiency.Methods: We examined retrospectively 28 children with pituitary insufficiency in the Endocrinological department of University hospital (Minsk) over 2001–2013 years. Group 1 (G1) - children with multiple acquired pituitary insufficiency (MAPI) after brain tumors treatment (11 children (73.3%) underwent surgical, 4 (26.7%) - combined treatment: surgical and radiation ...

Objective: Determination of changes in metabolic status and osteoprotegerin concentrations in obese children.Methods: We examined 221 children in the University Hospital (Minsk) from 2017 to 2019 yrs. Their anthropometric parameters (height, weight, body mass index (BMI)) were determined. Blood levels of osteoprotegerin (OPG), insulin were determined. In the biochemical blood test, the parameters of uric acid, insulin were evaluated. All children were di...

Objective: Determination of changes in metabolic status and vitamin D, osteoprotegerin concentrations in obese children.Methods: We examined 221 children in the University Hospital (Minsk) from 2017 to 2019 yrs. Their anthropometric parameters (height, weight, body mass index (BMI)) were determined. Blood levels of vitamin D, osteoprotegerin (OPG), insulin were determined. In the biochemical blood test, the parameters of uric acid, glucose were evaluated...

Aim: To evaluate bone mineral density (BMD) and its relationship with calcium (Ca) and phosphorus (P) metabolism in children with obesity.Methods: We examined 105 children in the University Hospital (Minsk) from 2011 to 2015 yrs. Their anthropometric parameters (height, weight, BMI) were determined. Body composition with evaluating of mineral component were made by dual energy X-ray absorptiometry with the calculation of feet, hands, spine, ribs, hips BM...

Objectives: The prevalence of diabetes mellitus type 1 (DM 1) had increased nowadays in children in Belarus. Psychological problems are one of side-effects of the disease.Aim: To determine the presence of psychological problems in children with DM 1.Methods: We examined 45 children (boys – 23, girls – 22) age 14.4±0.8 years, with DM 1 in University hospital (Minsk) in 2014–2015 years. All children underwent psyc...

Background: The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D2 receptor binding (Thompson et al., 1997; Pohjalainen et al.,1998). Associations between Taq1A polymorphism DRD2/ANKK1 gene and reward sensitivity including compulsive overeating were reported (Propper et al., 2008; Davis et al., 2008). To study the association of DRD2/ANKK1 Taq1A polymorphism (rs1800497) with obesity we started g...

Background: Social adaptation difficulty is one of the serious complications in obese children. It manifests with the complex of emotional and behavioral disorders.Aim: To estimate the peculiarities of psychological status, frequency, and severity of depressive disorders in obese children.Methods: We examined 242 children in the in the Endocrinological Department of University Hospital (Minsk); group 1 – 152 obese children (BM...

Background: Binge eating (BE) is a common cause of severe paediatric obesity, which develops after the uncontrolled wish of changing the present emotional condition.Aim: To study the phenomenon of BE in the context of emotional disorders in severe obese children.Methods: We examined 88 children with severe obesity (mean±s.d. 11.5±3.4 years; BMI 29.7±5.7 kg/m2) in the Endocrinological Department of Universi...